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pcrB [2017-8-11 16:0:3]
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pcrB [2017-8-11 16:0:3]

heptaprenylglyceryl phosphate synthase
locus
BSU06600
pI
4.20
mw
24.94 kDa
protein length
228 aa Sequence Blast
gene length
684 bp Sequence Blast
function
unknown
product
heptaprenylglyceryl phosphate synthase
essential
no
synonyms
yerE

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.4|Lipid metabolism] → [category|SW 2.4.3|Lipid metabolism/ other]
  • Gene

    Coordinates
    718,622 → 719,308

    The protein

    Catalyzed reaction/ biological activity

  • production of heptaprenylglyceryl phosphate from heptaprenyl diphosphate and glycerol-1-phosphate [Pubmed|23322418]
  • Protein family

  • GGGP synthase family (according to Swiss-Prot)
  • Structure

  • [PDB|1VIZ] [Pubmed|23322418]
  • Expression and Regulation

    Operons

    genes
    [gene|0BA7EC658F5C2397A90B68AC234D04966966561C|pcrB]-[gene|C73E52D214E24F21696973B19B0A44CE785D6FBA|pcrA]-[gene|03EFF93C1B0CE075AE068ECC4EDE9BE5D03C857E|ligA]-[gene|ADAE6B5C301959D90592A6F26DFE1690BF6F5552|yerH]
    description
    [Pubmed|9701819]

    regulatory mechanism

  • [protein|D267AF38B0CF107042326E9B8F3DD3C9C85840E4|LexA]: repression, [Pubmed|16267290], in [regulon|D267AF38B0CF107042326E9B8F3DD3C9C85840E4|LexA regulon]
  • regulation

  • induced by DNA damage ([protein|search|LexA]) [Pubmed|16267290]
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    Biological materials

    Mutant

  • MGNA-A926 (yerE::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/926 NBRP B. subtilis, Japan]
  • References

  • 9701819,22614947,21761520,18558723,23322418,24684232